C-Reactive Protein (CRP) is one of the galectins that is best known as an acute phase reactant. CRP is released by the body in response to acute injury, infection, or other inflammatory stimuli.
Positive association between CRP and coronary artery disease. In a survey of 388 British men aged 50-69, the prevalence of coronary artery disease increased 1.5 fold for each doubling of CRP level.
The CRP gene is located on the first chromosome (1q21-q23).
CRP is a member of the class of acute phase reactants as its levels rise dramatically during inflammatory processes occurring in the body. It is thought to assist in complement binding to foreign and damaged cells and affect the humoral response to disease. It is also believed to play an important role in innate immunity, as an early defense system against infections.