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In human genetics, Haplogroup F* (M89) is a Y-chromosome haplogroup (Note: due to technical restrictions, the title of this page does not contain an "*").

This haplogroup first appeared in Africa some 45,000 years before present. It is believed to represent the "second-wave" of expansion out of Africa.

Haplogroup F* is an ancestral haplogroup to Y-chromosome haplogroups G (M201), H (M52), I (M170), J (12f2.1), and K (M9) along with its descendant haplogroups (L, M, N, O, P, Q, and R).

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