Genomics
See Also
Description
- Gene type: protein coding
- Gene name: NEUROD2
- Gene description: neurogenic differentiation 2
- Chromosome: 17; Location: 17q12
- Organism: Homo sapiens
- Gene aliases: NDRF; MGC26304
Summary
This gene encodes a member of the neuroD family of neurogenic basic helix-loop-helix (bHLH) proteins. Expression of this gene can induce transcription from neuron-specific promoters, such as the GAP-43 promoter, which contain a specific DNA sequence known as an E-box. The product of the human gene can induce neurogenic differentiation in non-neuronal cells in Xenopus embryos, and is thought to play a role in the determination and maintenance of neuronal cell fates.
Discussion
NeuroD2 is necessary for development and survival of central nervous system neurons. [1]
A possible impact of the neuroD2 transcription factor on the development of drug abusing behavior. [2]
Links
