THE COMPOSITION OF SPECIFIC PRECIPITATES IN THE REGION OF ANTIGEN EXCESS
Saul Malkiel 1 and William C. Boyd Ph.D.
The Journal of Experimental Medicine, Vol 66, 383-396, Copyright, 1937, by The Rockefeller Institute for Medical Research New York
From Boston University School of Medicine, and Evans Memorial, Massachusetts Memorial Hospitals, Boston
Data are given, for seven different antisera, for the composition of the specific precipitate as a function of the relative proportions of antiserum and antigen used. In the region of antigen excess, a linear relation is found between the ratio of antibody to antigen in the precipitate and the amount of antiserum used. The significance of these results, particularly in their bearing on theories of the precipitin reaction, is discussed.
Submitted on May 27, 1937